Young and Full of Fluff

When I like a show, I usually watch the special features on the DVDs. And, of course, the cast almost always says that they have fantastic chemistry and that's so rare to find. (Just like featurettes on fantasy films always say that the world is "so real" and sci fi films always say that what they're doing has never been done before.)

So, in light of the actually honest interview by Robert Pattinson of Twilight, on what shows do the actors have really bad chemsitry with each other?

I'll start--CSI:Miami. Anyone else want to weigh in?